Mathematical Biology Laboratory Department of Biology, Kyushu University

Joung-Hun Lee

NAME

Joung-Hun Lee

Email: clinamen2013[at]gmail.com
          traum98[at]bio-math10.biology.kyushu-u.ac.jp
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CURRENT POSITION

Visiting Assistant Professor, Department of Biology, Faculty of Science, Kyushu University

EDUCATION

  • March 1999 – June 2003, Ajou university, South Korea. Economics.
  • March 2005 – February 2007, Seoul National university, South Korea. Environmental management.
  • April 2010 – March 2013, Kyushu University, Japan. Biology.

RESEARCH INTERESTS

My research interest is resource management and I have built simple models that focus on resource users’ behavior or decision-making. For sustainable resource use, it is important to foster cooperative behavior because people (resource users or stakeholders)’s response can make difference in resource use. Previous projects applied a. widely accepted approach based on benefit maximization, b. searched way to enhance cooperative behavior, c. heterogeneity among people when they adjust strategies for improving their own benefit. Study of resource management raises critical problems in our society such as property right, rule crafting, punishment, etc which are essential for understanding of cooperation. Next goal in my study will be related those fundamental questions.

This figure illustrates the main result of the recent work (published in J. Theor. Biol.) which discusses the scheme of punishment, called graduated sanction. Sanction takes a greatly important rule for cooperation maintenance by affecting payoff function of each player. Long-lasting common resource management has known to have such a scheme of sanction (Ostrom, 1990) but this is not well explained in theoretical studies. We suggest conditions where this rule of sanction works efficiently with the assumption of pool punishment.

PUBLICATIONS

(7) Agent-based mapping of credit risk for sustainable microfinance, PLOS ONE, in press, (2015), Joung-Hun Lee. M. Jusup, B. Podobnik, Y. Iwasa.
(6) Coupled social and ecological dynamics of herders in Mongolian rangelands, Ecological Economics (2015), 114: 208-217. Joung-Hun Lee, K. Kakinuma, T. Okuro, Y. Iwasa.
(5) Games of corruption: How to suppress illegal logging, Journal of Theoretical Biology (2015), 367:1-13. Joung-Hun Lee, K. Sigmund, U. Dieckmann, Y. Iwasa.
(4) Modeling socio-economic aspects of ecosystem management and biodiversity conservation. Population Ecology (2014), 56: 27-40. Joung Hun Lee and Yoh Iwasa.
(3) Graduated punishment is efficient in resource management if people are heterogeneous. Journal of Theoretical Biology (2013), 333: 117-125, Yoh Iwasa and Joung Hun Lee.
(2) Optimal investment for enhancing social concern about biodiversity conservation: A dynamic approach, Theoretical Population Biology (2012), 82: 177-186. Joung Hun Lee and Yoh Iwasa
(1) J.H. Lee and Y. Iwasa. Tourists and traditional divers in a common fishing ground, Ecological Economics. 70(12): 2350-2360 (2011).

Kayoko Ohta

NAME

Kayoko Ohta

CURRENT POSITION

Technical assistant, Department of Biology, Faculty of Science, Kyushu University

PUBLICATIONS

(3) Chakraborty T, Mohapatra S, Tobayama M, Ohta Ka, Ryu YM, Kazeto Y, Ohta Ko, Zhou L, Nagahama Y, Matsubara T, Hatching enzymes disrupt aberrant gonadal degeneration by the autophagy/apoptosis cell fate decision. Sci Rep. 2017, 7(1):3183
(2) Kurta (Ohta) K, Burgess SM, Sakai N. Transgenic zebrafish produced by retroviral infection of in vitro-cultured sperm. PNAS 2004, 101(5): 1263-7
(1) Kurta (Ohta) K, Sakai N. Functionally distinctive testicular cell lines of zebrafish to support male germ cell development. Mol Reprod Dev. 2004, 67(4): 430-8

NAME

Masashi Iwamoto

Email: miwamoto[at]nih.go.jp
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CURRENT POSITION

Visiting Assistant Professor, Department of Biology, Faculty of Science, Kyushu University

PUBLICATIONS

(10) Iwamoto M, Cai D, Sugiyama M, Suzuki R, Aizaki H, Ryo A, Ohtani N, Tanaka Y, Mizokami M, Wakita T, Guo H, Watashi K: Functional association of cellular microtubules with viral capsid assembly supports efficient hepatitis B virus replication. Sci. Rep. 7(1): 10620 (2017).
(9) Shimura S, Watashi K, Fukano K, Peel M, Sluder A, Kawai F, Iwamoto M, Tsukuda S, Takeuchi S J, Miyake T, Sugiyama M, Ogasawara Y, Park SY, Tanaka Y, Kusuhara H, Mizokami M, Sureau C, Wakita T: Cyclosporin derivatives inhibit hepatitis B virus entry without interfering with NTCP transporter activity. J Hepatol. 66: 685-692 (2017)
(8) Tsukuda S, Watashi K, Hojima T, Isogawa M, Iwamoto M, Omagari K, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Sureau C, Wakita T: A new class of hepatitis B and D virus entry inhibitors, proanthocyanidin and its analogs, that directly act on the viral large surface proteins. Hepatology, 65: 1104-1116 (2017)
(7) Kaneko S, Kakinuma S, AsahinaY, Kamiya A, Miyoshi M, Tsunoda T, Nitta S, Asano Y, Nagata H, Otani S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Nakauchi H, Nishitsuji H, Ujino S, Shimotohno K, Iwamoto M, Watashi K, Wakita T,& Watanabe M:Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus. Sci. Rep. 6: 29358 (2016).
(6) Nishikori S, Takemoto K, Kamisuki S, Nakajima S, Kuramochi K, Tsukuda S, Iwamoto M, Katayama Y, Suzuki T, Kobayashi S, Watashi K, Sugawara F: Anti-hepatitis C Virus Natural Product from a Fungus, Penicillium herquei. J Nat Prod. 79: 442-6 (2016)
(5) Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H,  Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T: A novel tricyclic polyketide, vanitaracin A, specifically inhibits the entry of hepatitis B and D viruses through targeting NTCP. J Virol. 89: 11945-53 (2015)
(4) Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.: Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression. J Biol Chem. 290: 5673-5684 (2015)
(3) Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T.: Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter NTCP. Hepatology, 59: 1726-1737 (2014)
(2) Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T.: Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP. Biochem Biophys Res Commun. 443: 808-813 (2014)
(1) Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T.: Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID). J Biol Chem. 288: 31715-31727 (2013)

Review

(2) Tsukuda S+, Iwamoto M+, Koichi Watashi : NTCP (sodium taurocholate cotransporting polypeptides). Encyclopedia of Signaling Molecules, 2nd Edition (2017). (+equally contribution)
(1) Iwamoto M and Watashi K: Closing the door on hepatitis B and D virus entry: what are our therapeutic options? . Future Virol. 11 (11): 715-718 (2016).

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