九州大学数理生物学研究室

李 貞憲(り じょんふぉん)

李 貞憲(り じょんふぉん)

所属:九州大学理学研究院生物科学部門数理生物学研究室

役職:特任助教

所属学会:日本生態学会、日本数理生物学会

連絡先:clinamen2013[at]gmail.com
          traum98[at]bio-math10.biology.kyushu-u.ac.jp
※[at]を@に置き換えて下さい。

略歴

2007年 2月 ソウル国立大学 環境大学院 卒業
2010年 4月〜 九州大学大学院システム生命科学府 数理生物学研究室

研究内容

My research interest is related to environmental problem, biodiversity conservation, poverty, conflicts between people and its resolution. Although those seem different, from the perspective that we can somehow control or at least alleviate suffering from those problems based on our decision to allocate or use our resource, they are connected, so that my academic interest is resource management or allocation, so called, sustainable science. I use very simple dynamics of ecology and human decision until recently which is useful for synchronization of two aspects. The projects I have studied are (1) the resource management of common fishing ground including the possible conflicts which can be caused by new resource usage, (2) optimal allocation of funds for biodiversity between awareness-raising activities of people about biodiversity and direct conservation activities, (3) the optimal level of punishment the role of which has been intensely discussed but the mechanism to decide the level has not yet studied that much despite its importance.

業績

(7) Agent-based mapping of credit risk for sustainable microfinance, PLOS ONE, in press, (2015), Joung-Hun Lee. M. Jusup, B. Podobnik, Y. Iwasa.
(6) Coupled social and ecological dynamics of herders in Mongolian rangelands, Ecological Economics (2015), 114: 208-217. Joung-Hun Lee, K. Kakinuma, T. Okuro, Y. Iwasa.
(5) Games of corruption: How to suppress illegal logging, Journal of Theoretical Biology (2015), 367:1-13. Joung-Hun Lee, K. Sigmund, U. Dieckmann, Y. Iwasa.
(4) Modeling socio-economic aspects of ecosystem management and biodiversity conservation. Population Ecology (2014), 56: 27-40. Joung Hun Lee and Yoh Iwasa.
(3) Graduated punishment is efficient in resource management if people are heterogeneous. Journal of Theoretical Biology (2013), 333: 117-125, Yoh Iwasa and Joung Hun Lee.
(2) Optimal investment for enhancing social concern about biodiversity conservation: A dynamic approach, Theoretical Population Biology (2012), 82: 177-186. Joung Hun Lee and Yoh Iwasa
(1) J.H. Lee and Y. Iwasa. Tourists and traditional divers in a common fishing ground, Ecological Economics. 70(12): 2350-2360 (2011).

山本 君代

山本 君代(やまもと きみよ)

所属:
九州大学  数理生物学教室 学術研究員
Harvard School of Public Health, Department of Biostatistics and Computational Biology, Research Fellow
大阪医科大学 一般消化器外科学教室 非常勤講師

連絡先:kyamamoto[at]kyushu-u.org
※[at]を@に置き換えて下さい。

略歴

-H20 京都大学付属病院、勤務医
H24 大阪医科大学医学研究院、博士(医学)取得
H24- 日本学術振興会特別研究員PD後、現職

研究内容

様々な固形癌の臨床像を数理モデル化する研究に興味があります。

疾患の診断治療に対し、基礎医学的研究や臨床経験、勘だけに頼らない、新たな視点からのcriteriaを示唆出来ればと思います。

業績

(13) Kimiyo N. Yamamoto, Masatsugu Ishii, Yoshihiro Inoue, Fumitoshi Hirokawa, Ben MacArthur, Akira Nakamura, Hiroshi Haeno, and Kazuhisa Uchiyama. Prediction of postoperative liver regeneration from clinical information using a data-led mathematical model. Sci. Rep. 2016. (accepted)
(12) Yamamoto KN, Nakamura A, and Haeno H. The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes. Sci. Rep. 5:15886(2015).
(11) Kobayashi H, Kobayashi CI, Nakamura-Ishizu A, Karigane D, Haeno H, Yamamoto KN, Sato T, Ohteki T, Hayakawa Y, Barber GN, Kurokawa M, Suda T, and Takubo K. Bacterial c-di-GMP Affects Hematopoietic Stem/Progenitors and Their Niches through STING. Cell Rep. 11(1):71-84(2015).
(10) Yamamoto KN, Hirota K, Takeda S, and Haeno H. Evolution of Pre-Existing versus Acquired Resistance to Platinum Drugs and PARP Inhibitors in BRCA-Associated Cancers. PLoS One. 9(8):e105724(2014).
(9) Fujita M, Sasanuma H, Yamamoto KN, Harada H, Kurosawa A, Adachi N, Omura M, Hiraoka M, Takeda S, and Hirota K. Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks. PLoS One. 8(4):e60043(2013).
(8) Yamamoto KN and Taniguchi M. Cross ratio coordinates for the deformation spaces of a marked Möbius group. Conform. Geom. Dyn. 17:145-154(2013).
(7) Qing Y, Yamazoe M, Hirota K, Dejsuphong D, Sakai W, Yamamoto KN, Bishop DK, Wu X, and Takeda S. The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. PLoS Genet. 7(7):e1002148(2011).
(6) Yamamoto KN, Hirota K, Kono K, Takeda S, Sakamuru S, Xia M, Huang R, Austin CP, Witt KL, and Tice RR. Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines. Environ Mol Mutagen. 52(7):547-61(2011).
(5) Yamamoto KN, Kobayashi S, Tsuda M, Kurumizaka H, Takata M, Kono K, Jiricny J, Takeda S, and Hirota K. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Proc Natl Acad Sci U S A. 108(16):6492-6(2011).
(4) Evans TJ, Yamamoto KN, Hirota K, and Takeda S. Mutant cells defective in DNA repair pathways provide a sensitive high-throughput assay for genotoxicity. DNA Repair (Amst). 10;9(12):1292-8(2010).
(3) Tanida E, Usuda K, Kono K, Kawano A, Tsuji H, Imanishi M, Suzuki S, Ohnishi K, and Yamamoto K. Urinary scandium as predictor of exposure: effects of scandium chloride hexahydrate on renal function in rats. Biol Trace Elem Res. 130(3):273-82(2009).
(2) Ariyoshi Y, Shimahara M, Okutomi T, Fujimoto T, Shimahara S, Kono K, Dote T, Usuda K, Shimizu H, Yamadori E, and Yamamoto K. Intravenous Bisphosphonate-related Osteonecrosis of the Jaws. Bulletin of the Osaka Medical College. 55(2):91-98(2009).
(1) Usuda K, Tanida E, Tsuji H, Imanishi M, Suzuki S, Takasaki K, Yamamoto K, Onishi K, and Kono K. Content of Fluoride in Bottled Mineral Water Sold in Japan. Biomed Res Trace Elements. 19:254-259(2008).

日本語総説

(4) 波江野洋、山本君代. がん進展仮定における薬剤耐性獲得の数理モデル. がん分子標的治療.12(3)(2014).
(3) 波江野洋、山本君代. がんにおける突然変異蓄積過程の数理モデル解析. 実験医学増刊. 32(12)(2014).
(2) 山本君代,河野公一,谷口善仁. 遺伝薬理学的手法を利用した化学 物質の変異原性と抗癌剤シーズのハイスループットスクリーニング法. 細胞工学. 29(1)(2010).
(1) 清水宏泰, 山本君代. がん対策基本法. Modern Physician. 30(10):1282-1283(2010).

現在・過去の競争的研究資金

(2) 平成28年度 日本学術振興会科学研究費 基盤C (研究代表者)
(1) 平成28年度 大阪医科大学研究拠点育成奨励助成金 (分担者)

Cinthia Marie Tanaka

Cinthia Marie Tanaka

所属:サンパウロ大学

役職:訪問研究生

連絡先:cimarie[at]gmail.com
※[at]を@に置き換えて下さい。

略歴

2010年 7月 サンパウロ大学 卒業(分子科学)
2012年 8月 - 現在 サンパウロ大学 Ph.D.課程(応用数学)

研究内容

[1] Cultural evolution/evolution of cooperation

[2] Evolutionary game theory

業績

(1) Tanaka, C. M. and Iwasa, Y. (2012, September). Cultural evolution of a belief controlling human mate choice: Dynamic modeling of the hinoeuma superstition in Japan. Journal of Theoretical Biology 309, 20–28.

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