Minisymposia

Special symposia

Minisymposia

Wednesday, Sep. 7

Time 9:00 - 10:30, Sep. 7
Room B

Special symposium

Complexity and coexistence of population in simple ecological systems

Organizers:

  • Malay Banerjee
    Department of Mathematics and Statistics, IIT Kanpur, Kanpur, INDIA
  • Yasuhiro TAKEUCHI
    Department of Physics and Mathematics, College of Science and Engineering, Ayoama Guykin University

Lotka-Volterra (LV) model is fundamental in population dynamics. The two-species LV model admits no isolated periodic orbits. It is known the three-species LV model can exhibit periodic and even chaotic dynamics (2 prey, one-predator case and prey-predator with intra-guild predation by the top predator). If we modify two-species LV type prey-predator by adopting Holling type II functional response, the model can have a periodic solution but the appearance of large amplitude limit cycles leads to the paradox of enrichment. Recently several interesting bifurcation scenarios have been found when the logistic growth for prey is substituted with growth including Allee effect. The purpose of the symposium is to summarize the complex dynamics known in simple population models and how the modification of functional response or the growth with Allee effect or inclusion of maturation delay can change the bifurcation scenario. Also we discuss on the effect given by these modifications on the stable coexistence and persistence of population.

Presenters and Titles:

Toshiyuki Namba

Department of Biological Science, Graduate School of Science, Osaka Prefecture University

Coexistence of predators in simple ecological systems of intra-guild predation

Yasuhiro Takeuchi

Department of Physics and Mathematics, College of Science and Engineering, Ayoama Guykin University

Maturation delay for the predators can enhance stable coexistence in prey-predator model with Allee effect

Malay Banerjee

Department of Mathematics and Statistics, IIT Kanpur

Maturation delay can stabilize the prey-predator dynamics

Time 9:00 - 10:30, Sep. 7
Room D

Structure-based control of complex network systems

Organizer:

  • Atsushi Mochizuki
    Theoretical Biology Laboratory, RIKEN

Controlling complex biological systems is one of the most important missions in basic biology and medical science. Especially in regenerative medicine, it is strongly required to establish non-empirical methods to regenerate cells or tissues artificially. Experimental methods have provided large information on interactions between bio-molecules. However, such network information is not sufficient to specify detail of the dynamics of systems. Recently, different theoretical methods were proposed independently, by which rational criteria to choose key nodes for controlling whole systems are given from structure of networks alone. In this symposium, we invite advanced researchers studying theoretical methods to control complex network systems. We discuss mathematical and practical aspects of these methods, and consider possible improvement and collaborations between different methods.

Presenters and Titles:

Tatsuya Akutsu

Kyoto University

Minimum Dominating Set-Based Approaches for Controlling and Analyzing Biological Networks

Ying-Cheng Lai

Arizona State University

Tipping point in networked dynamical systems: control, recovery, and early warnings

Jorge Gómez Tejeda Zañudo

Pennsylvania State University

Cell fate reprogramming by control of intracellular network dynamics

Atsushi Mochizuki

RIKEN

Controlling regulatory networks by feedback vertex sets

Time 9:00 - 10:30, Sep. 7
Room E

Biological oscillations at diverse spatiotemporal scales

Organizers:

  • Takayuki Ohara
    Graduate School of Environmental Science, Hokkaido University
  • Akiko Satake
    Department of Biology, Faculty of Science, Kyushu University

Periodic or chaotic oscillations are observed in diverse biological phenomena at different spatiotemporal scales ranging from gene expression to mass flowering of forests.

These rhythmic phenomena are directly connected with the fitness of organisms, e.g. rhythmic patterns of plant starch metabolism to avoid carbon starvation.

In this session, recent findings about biological oscillations at different scales including cellular circadian rhythms of plants and mammals, growth patterns of plant tissue, and synchronization of plant reproduction will be presented.

The purpose of the session is (i) to provide the audiences with diverse topics of biological rhythms, and (ii) to develop our understanding of the oscillation phenomena by sharing different viewpoints obtained from the studies of distinct spatiotemporal scales.

Presenters and Titles:

Tomoaki Muranaka

Nagoya University

The plant circadian clock as a multi-oscillator system

Takayuki Ohara

Hokkaido University

Phase response of circadian clocks optimizes the growth of Arabidopsis thaliana

Sungho Hong

OIST

GABA-mediated phase couplings and seasonal time coding in the suprachiasmatic nucleus

Akiko Satake

Kyushu University

Parameterization and validation of a resource budget model for masting using spatiotemporal flowering data of individual trees

Time 10:45 - 12:15, Sep. 7
Room B

Cancer Modeling

Organizer:

  • Hiroshi Haeno
    Kyushu University

In the field of cancer research, the demand of mathematical and theoretical analysis has recently been increasing. Based on tons of genomic data and tumor growth data with/without drugs, lots of mathematical and statistical models have been investigated for revealing the theory of cancer dynamics and evolution. In this symposium, we will present the up-to-date mathematical models of cancer based on experimental and clinical data and spread the opportunities that theoretical researchers study cancer.

Presenters and Titles:

Hiroshi Haeno

Kyushu University

The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes

Munechika Misumi

Radiation Effects Research Foundation

Cancer risk of Japanese Atomic bomb survivors: challenge in radiation epidemiology to investigate radiation carcinogenesis

Lin L. Liu

Harvard University

A unified framework to model induced stem cell - a case study of generalized multi-type branching process and beyond

Kimiyo N. Yamamoto

Kyushu University

Computational Modeling of Individualized Management in Pancreatic Adenocarcinoma

Time 10:45 - 12:15, Sep. 7
Room D

Network and Timeline: Recent Topics in Complex Networks

Organizers:

  • Takaaki Aoki
    Faculty of Education, Kagawa University
  • Satoru Morita
    Department of Mathematical and Systems Engineering, Shizuoka University

The purpose of this symposium is to bring together some new topics in network science, which are expected to be associated with mathematical biology. We will discuss possibility of new models of temporal networks, adaptive networks and epidemics on networks.

Presenters and Titles:

Takaaki Aoki

Kagawa University

Burst behavior and scale-free network emerging in adaptive temporal Networks

Tomokatsu Onaga

Kyoto University

Controlling the emergence of event cascades in inhomogeneous networks

Taro Takaguchi

National Institute of Information and Communications Technology

On uncertainty of epidemic spreading in complex networks

Satoru Morita

Shizuoka University

Comparison among several types SIS epidemic models on networks

Time 16:15 - 17:45, Sep. 7
Room B

Cancer evolution

Organizer:

  • Kimiyo N. Yamamoto
    Kyushu University

Cancer progression can be considered as the consequences of evolution. Recently, lots of genomic data have been acquired due to the advancement of sequencing technologies, and research of the evolutionary process of cancer by genomic analysis and mathematical modeling is in attention. In this symposium, we will present the up-to-date mathematical and statistical analysis with experimental and clinical data and spread the opportunities that theoretical researchers study cancer.

Presenters and Titles:

Subhajyoti De

Rutgers University

TBA

Yoichiro Yamamoto

Shinshu University

Tumor and immune cell dynamics explain the PSA bounce after prostate cancer brachytherapy

Benjamin Werner

Cancer Research UK

Identification of neutral tumor evolution across cancer types

Time 16:15 - 17:45, Sep. 7
Room D

Ecosystem Dynamics and Management

Organizers:

  • Yoh Iwasa
    Department of Biology, Faculty of Science, Kyushu University
  • Joung-Hun Lee
    Center for Decision Sciences, Kyushu University

Many ecosystems on earth have been formed under strong human activity. For the sustainable management of natural resources to be successful, we need to understand the coupling between social economic aspects and ecological and resource sciences. This is particularly important given the demands of increasing global population, environmental change and rising living standards (which lead to increased demand for resources). Mathematical and computational modeling has a great potential to improve our understanding of many aspects that are difficult to predict otherwise. In this symposium, we introduce several examples of coupled socio-economic and resource models, we discuss their common features and differences, and the future of this increasingly important section of mathematical biology.

Presenters and Titles:

Yoh Iwasa

Kyushu University

Coupled social and ecological models for ecosystem management

Tae-Soo Chon

Pusan National University

Assessment of Communities Responding to Natural and Anthropogenic Variability in Aquatic Ecosystems

Cindy Hauser

University of Melbourne

Optimisation and statistics used in an Australian weed eradication program

Joung-Hun Lee

Kyushu University

Optimal management of tropical forests with high risk of illegal logging: role of agroforestry and profit sharing

Time 16:15 - 17:45, Sep. 7
Room E

Infectious diseases in structured populations

Organizers:

  • Yukihiko Nakata
    Department of Mathematics, Shimane University
  • Ryosuke Omori
    Research Center for Zoonosis Control, Hokkaido University

When describing the complex dynamics of infectious diseases in the real world, heterogeneity, such as spatial heterogeneity and individual heterogeneity, is always an issue. Tons of structured population models have been proposed so far, we need to know what kind of model can reveal what. In this symposium five speakers will talk about the state-of-art analyses of the dynamics of infectious diseases at different scales from within-host to between host communities using the different model descriptions.

Presenters and Titles:

Gouhei Tanaka

The University of Tokyo

Metapopulation epidemic models with heterogeneous patches

Koichi Saeki

SOKENDAI

Evolution of global and local viral infection in the structured SIS model

Diána Knipl

Department of Mathematics, University College London

Challenges in control strategies of spatially explicit epidemic models

Toshikazu Kuniya

Graduate School of System Informatics, Kobe University

Discretization approach for the global stability analysis of structured epidemic models

Takehisa Hasegawa

Department of Mathematics and Informatics, Ibaraki University

Outbreaks in the SIR epidemics with multiple seeds - a statistical physics approach

Thursday, Sep. 8

Time 9:00 - 10:30, Sep. 8
Room B

Towards data-driven mathematical biology

Organizers:

  • Joung-Hun LEE
    Mathematical Biology Laboratory, Department of Biology, Kyushu University
  • Marko JUSUP
    Center of Mathematics for Social Creativity, Hokkaido University

Mathematical biology is often driven by purely theoretical considerations. Although theoretical contributions in themselves are extremely valuable, there is a huge potential for mathematical biology to add value to existing and new empirical data. To realize this potential it is necessary to open up a continuous dialogue between experimentally and theoretically oriented researchers from various disciplines who share the interest in biology. The proposed mini-symposium is intended to establish such a dialogue by illustrating several interesting case studies which greatly benefited, or could benefit, from mathematical modeling. Challenging questions are posed for future developments.

Presenters and Titles:

Madeleine Beekman

The University of Sydney

Different bees, different needs – nest site selection in honeybees

Kazunori Yamahira

Tropical Biosphere Research Center, University of the Ryukyus

Life-history adaptations and the latitudinal diversity gradient in medaka fishes

Takashi Kitagawa

The University of Tokyo

Electronic tagging applications and migration of Pacific bluefin tuna, Thunnus orientalis

Yoshinori Aoki

The University of Tokyo

Change in energy intake and cost of skipjack tuna (Katsuwonus pelamis) with northward migration in the western North Pacific

Commentators:

Cindy Hauser

University of Melbourne

Marko Jusup

Hokkaido University


Time 9:00 - 10:30, Sep. 8
Room D

Mathematical modeling for viral infections within host

Organizer:

  • Yusuke Kakizoe
    Systems Life Sciences, Graduate school of Kyushu University

Mathematical model of viral infections has a very important role in our quantitative understanding of viral dynamics. For instance, we can estimate the pathogenesis of viruses, evaluating the efficacy of anti viral drugs, predicting the viral dynamics, etc. In this symposium, we will present recent advances of mathematical modeling for viral infections.

Presenters and Titles:

Yusuke Kakizoe

Graduate School of Systems Life Sciences, Kyushu University

Modeling to quantify HIV-1 entry

Alexey Martyushev

Department of Biology, Faculty of Sciences, Kyushu University

Epitope-specific CD8+ T cell kinetics rather than viral variability determines the timing of immune escape in SIV infection

Laura Liao

Department of Physics, Ryerson University

The impact of influenza A defective interfering particles on plaque assays

Catherine Beauchemin

Department of Physics, Ryerson University

Something is wrong with the respiratory syncytial virus

Time 9:00 - 10:30, Sep. 8
Room E

Plant phenotyping with morphometrics

Organizer:

  • Koji Noshita
    Graduate School of Agriculture and Life Science, The University of Tokyo

With recent advancements in genotyping, phenotyping is now a bottleneck in development of several research fields in plant science (e.g. agricultural science, developmental and evolutionary biology). Particularly, morphological properties are the most important information but hardest to treat in plant phenotyping. Morphometrics is one of the candidates to relieve the bottleneck by providing quantifying, visualizing, analyzing and summarizing techniques. In this minisymposium, we focus on how to understand and interpret the morphological data of plants with genomic, developmental, and physiological information.

Presenters and Titles:

Koji Noshita

The University of Tokyo

Leaf surface reconstruction from “noisy” point cloud data for geometric analysis

Dan Chitwood

Donald Danforth Plant Science Center

Morphometric analysis of leaves

Wei Guo

Institute for Sustainable Agro-ecosystem Services, The University of Tokyo

Low cost field based plant phenotyping with cameras and image analytics

Time 10:45 - 12:15, Sep. 8
Room B

Horizon of mutualism studies

Organizer:

  • Hisashi Ohtsuki
    SOKENDAI (The Graduate University for Advanced Studies)

Evolution of mutualism and its ecological consequences have recently been drawing a wider attention. For example, it is not obvious how mutualism is initially established between different species with different interests, how the evolutionary transition from parasitism to mutualism occurs, and how mutualism is stably maintained despite the possibility of exploitation by cheaters. In community ecology, it has been theoretically shown that mutualism destabilizes the community. This symposium aims to provide recent theoretical findings in mutualism studies and discuss future direction in this field.

Presenters and Titles:

Jonas Schluter

Memorial Sloan Kettering Cancer Center

The ecology of the microbiome: Networks, competition and cooperation, and stability

Hideo Ezoe

Osaka Prefecture University

Coevolutionary dynamics of one-to-many mutualisms

Yu Uchiumi

SOKENDAI

Resampling after discrimination destabilizes mutualism

Atsushi Yamauchi

Center for Ecological Research, Kyoto University

Joint evolution of interspecific mutualism and developmental stability under directional selection in trait space

Time 10:45 - 12:15, Sep. 8
Room D

Patterns and Dynamics in Partial Differential Equations appearing in Mathematical Biology

Organizer:

  • Toshiyuki Ogawa
    Meiji University

Recent developments of the analysis for the PDE model relating to mathematical biology are discussed in this mini-symposia. Four speakers introduce reaction-diffusion approximation for non-local effects, amoeba behaviour, 2-dimensional traveling wave composed of convex curves and drift bifurcation of traveling waves.

Presenters and Titles:

Hirokazu Ninomiya

Meiji University

Pattern formation through non-local interactions

Keiichi Ueda

University of Toyama

Differentiation of behavioral type induced by environmental variations in an amoeba

Harunori Monobe

Tokyo Institute of Technology

Convex traveling wave solutions to an interface equation

Toshiyuki Ogawa

Meiji University

Bifurcation of traveling wave in Competition-Diffusion equations

Time 10:45 - 12:15, Sep. 8
Room E

Extraordinary forms - exploring the limits of cell shape modeling

Organizers:

  • Shigeo Hayashi
    Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology
  • Takashi Miura
    Department of Anatomy and Cell Biology, Kyushu University Graduate School of Medicine
  • Co-presented by Spontaneous pattern formation ex vivo, JST CREST

Cells have been extensively studied as a building block of living organisms in cell biology and mathematical biology. As a result, morphogenesis of standard cells like epithelia, fibroblasts or neurons are gradually understood. However, cells exhibit much diverse shape in the real world. In this symposium, we present several strange cell shapes which we cannot imagine from textbook knowledge together with current theoretical models that has been used to model cell form. By combining these biological examples and theoretical models, we try to clarify the possibility and limit of cell shape modeling in mathematical biology.

Presenters and Titles:

Takashi Miura

Kyushu University Graduate School of Medical Sciences

Mechanism of jigsaw-puzzle pattern formation in plant leaf epidermal cell: modeling single cell shape by interface equation and convolution kernel

Hideki Takahashi

The University Museum, Hokkaido University

Form and Function of Pollen Grains

Ryuichi Nishinakamura

Institute of Molecular Embryology and Genetics, Kumamoto University

Recreating human podocytes in the kidney

Hideru Togashi

Kobe University Graduate School of Medicine

Cellular Tessellation in Sensory Epithelia

James Glazier

Department of Intelligent Systems Engineering and Biocomplexity Institute, Indiana University

Simulating the Onset and Development of Polycystic Kidney Disease using Virtual Tissues

Time 15:45 - 17:15, Sep. 8
Room B

Biological Relevances of Mathematical Models

Organizer:

  • Kunimochi Sakamoto
    Hiroshima University

The purpose of the symposium is to investigate, by three talks, whether or not dynamical system models for biological phenomena are really relevant to, or capture certain aspects of, the biological systems which the differential equations are originally intended to model. It is not intended to assert that our views are the definite ones. Through our talks, we attempt to set a stage for open discussion.

Presenters and Titles:

Kunimochi Sakamoto

Hiroshima University

Bulk reaction versus Boundary flux in diffusive systems

Fumio Nakajima

Iwate University

A mathematical approach to the economy of atomic power generation

Masataka Kuwamura

Kobe University

Diffusion driven destabilization of a spatially homogeneous limit cycle in reaction- diffusion systems

Time 15:45 – 17:15, Sep. 8
Room E

Special symposium

Pattern formation in heterogeneous environments

Organizers:

  • Izumi Takagi
    Institute of Liberal Arts and Sciences, Tohoku University
  • Fang Li
    Center for PDE, East China Normal University

Turing used the principle of diffusion-driven instability (DDI, for short) to explain how a spatially homogeneous state can develop spontaneously a spatially nontrivial structure, i.e., pattern. However, actual biological phenomena take place in more or less non-uniform environments. In some cases organisms themselves create non-uniformity of the environment. Therefore, it is very important to understand quantitatively the effect of spatial heterogeneity on resulting patterns.

The purpose of this symposium is to explore the frontiers of mathematical researches on models of pattern formation that utilize partial differential equations, laying emphasis on how spatial heterogeneity influences patterns. Moreover, this mini-symposium is co-organized by Japanese and Chinese mathematicians in the hope of promoting collaboration not only between biologists and mathematicians, but also collaboration among young scientists in Eastern Asia.

Presenters and Titles:

Izumi Takagi

Institute of Liberal Arts and Sciences, Tohoku University

Pattern formation in homogeneous media vs in heterogeneous media: cutting and grafting experiments on hydra

Huicong Li

Center for PDE, East China Normal University

Spiky steady states for a chemotaxis system with singular sensitivity

Sohei Tasaki

Frontier Research Institute for Interdisciplinary Sciences, Tohoku University

Self-organization of bacterial communities against environmental pH variation

Fang Li

Center for PDE, East China Normal University

Non-local effects in an integro-PDE model from population genetics

Friday, Sep. 9

Time 9:00 – 10:30, Sep. 9
Room B

Hans Meinhardt; The Loss of the Meister of Developmental Pattern Formation and Unachieved Discussions

Organizer:

  • Akiko Nakamasu
    Kyushu University
  • Co-presented by 3D morphologic, Scientific Research on Innovative Areas, JSPS

Hans Meinhardt was a giant and pioneer of mathematical biology in the field of developmental biology. He set up various mathematical models based on reaction-diffusion systems and was the first person who made systematic use of computer simulations in explanations of developmental phenomena. He had brought about positive impacts on this field; however we lost him last February. So, in this symposium scientists who have been working on subjects closely related to him get together and continue unachieved discussions with him. We will hope to deepen our understanding of current topics in the study of pattern formation and reaction-diffusion systems.

Presenters and Titles:

Izumi Takagi

Tohoku University

Mathematical beauty of the activator-inhibitor system

Shigeru Kondo

Osaka University

Simpler modelling of the biological pattern formation

Masayasu Mimura

Meiji University

Notion of diffusion-induced instability

Tatsuo Shibata

QBiC RIKEN

Pattern formation in chemotaxis cells and body axis formation

Time 9:00 – 10:30, Sep. 9
Room D

Special symposium

Unifying epidemiological and genomic approaches to infectious diseases
joint hosting symposium of the Japan Science and Technology Agency (JST) CREST big data application project “Detecting premonitory signs and real-time forecasting of pandemic using big biological data”

Organizers:

  • Yusuke Asai
    Hokkaido University
  • Hiroshi Nishiura
    Hokkaido University

Our special symposium highlights the halfway achievements of abovementioned project that excels into prediction and premonitory sign detection of pandemic, unifying epidemiological, genetic and other diverse datasets, supported by Japan Science and Technology Agency. The symposium aims to share a mixture of different mathematical modeling approaches to infectious diseases and enhance cutting edge collaborations among researchers who share common interest in handling infectious disease data. Especially, the organizers are pleased to have invited Dr Cornelia Pokalyuk from Germany to share important insights of population genetic modeling to evolutionary dynamics of viruses.

Presenters and Titles:

Cornelia Pokalyuk

Universität Magdeburg

The role of reinfection in a viral population subject to balancing selection

Hiroshi Nishiura

Hokkaido University

Mathematical modeling of MERS using epidemiological and genomic data

Yusuke Asai

Hokkaido University

Identifying the location of virus source by the effective distance approach

Kiyeon Kim

Research Center for Zoonosis Control, Hokkaido University

Estimating the population dynamics of influenza viruses from genomic data

Time 9:00 – 10:30, Sep. 9
Room E

Mathematical and statistical modeling to bridge the gap between empirical and theoretical research in ecology

Organizer:

  • Michio Kondoh
    Faculty of Science and Technology. Ryukoku University

Ecological systems are highly dynamic and complex across a range of organization levels from individuals to ecosystems and usually consist of interactions between different organization levels. Empirical data to reveal the ecological complexity is accumulating, thanks to long-term ecological monitoring and recent technical revolutions (metagenomics, transcriptomics and stable isotope analysis, for example). However, mechanistic understanding of ecological system is still not straightforward, partly due to the difficulties in identifying the interactions, or causalities, between entities occurring at multiple spatio-temporal scales. This is especially true when a controlled experiment is not possible - which is often the case in ecological studies of higher organization levels. In this session, recent development in mathematical or statistical modeling to overcome the difficulty and its application to empirical data of a range of organization levels will be introduced and discussed.

Presenters and Titles:

Chih-hao Hsieh

National Taiwan University

Empirical dynamic modeling for understanding and forecasting dynamic systems

Masayuki Ushio

Ryukoku University

Environmental triggers of general flowering in a tropical lowland forest in Borneo

Koji Iwayama

Ryukoku University

Imputation of RNA-seq data toward modeling transcriptome dynamics in a field

Takeshi Miki

National Taiwan University

Improved statistical recipe for evaluating microbial functional diversity from metabolic fingerprinting

Time 10:45 – 12:15, Sep. 9
Room B

The role of cost-benefit analysis in ecology and beyond

Organizer:

  • Marko Jusup
    Center of Mathematics for Social Creativity, Hokkaido University

To inform the audience of recent advances in our understanding of the cost-benefit analysis in biology, we discuss how mathematical modeling can help decision-making in various practical situations. The symposium is designed to be a fine example of how, using mathematics in the context of cost-benefit studies, we can extract unique and novel information that helps advance the knowledge in a number of subfields in biology (e.g. ecology, epidemiology, virology, etc.).

Presenters and Titles:

Tin Klanjscek

Ruđer Bošković Institute

Cost-benefit analysis to guide management of tourist activities in nature protected areas

Hiroyuki Matsuda

Yokohama National University

The tragedy of the mitigation policy on climate change

Zhen Wang

nterdisciplinary Graduate School of Engineering Sciences, Kyushu University

Statistical physics of vaccination

Time 10:45 – 12:15, Sep. 9
Room D

Recent development of Lyapunov functional approaches in mathematical biology

Organizers:

  • Yoichi Enatsu
    Department of Mathematical Information Science, Faculty of Science, Tokyo University of Science
  • Toshikazu Kuniya
    Graduate School of System Informatics, Kobe University

Recently, Lyapunov functional approaches for proving the global asymptotic stability of equilibria have been widely studied and developed by many researchers in the field of mathematical biology. The purposes of this minisymposium are to share and extend the knowledge on the theory of Lyapunov functions and their applications to mathematical models with various structures.

Presenters and Titles:

Connell McCluskey

Wilfrid Laurier University

Lyapunov functionals for delayed epidemic models

Jinliang Wang

School of Mathematical Science, Heilongjiang University

Dynamics of viral infection models incorporating cell-to-cell transmission

Tsuyoshi Kajiwara

Okayama University

Mathematical theory of the global stability of age-structured models for pathogen-immune interactions

Toru Sasaki

Okayama University

Asymptotic behaviour of solutions for a virus-immune dynamics model with diffusion

Yoji Otani

Okayama University

Lyapunov functionals for multi-group models with delay

Yasuhisa Saito

Shimane University

Lyapunov functions and some predator-prey differential equations

Time 10:45 – 12:15, Sep. 9
Room E

Geometry and Patterning in Tissue, Cell, and Nucleus

Organizers:

  • Yoshihiro MORISHITA
    Laboratory for Developmental Morphogeometry, RIKEN, Quantitative Biology Center
  • Sungrim SEIRIN LEE
    MLS, Hiroshima University

Mathematical studies have contributed to biology from different aspects. For example, one direct contribution is to find tendencies or rules by analyzing data, which can be bases for revealing mechanisms underlying focal phenomena. In addition to this, proving concepts by developing minimal models that can reproduce observations, and providing testable hypotheses or predictions for issues unsolved or difficult to experimentally approach. The purpose of this symposium is to show those different approaches to cellular and developmental biological phenomena with different theories such as differential geometry, cellular mechanics, and dynamical system.

Presenters and Titles:

Yoshihiro MORISHITA

RIKEN

An equation of chemical field to be satisfied for achieving optimal encoding of positional information during organ development

Masatoshi NISHIKAWA

Hosei University

Controlling contractile instabilities in the actomyosin cortex

Sungrim SEIRIN LEE

Hiroshima University

A challenging interdisciplinary approach to elucidate a mystery of remodeling process in nuclear architecture (Part I: Theory)

Hiroshi OCHIAI

PRESTO, JST

A challenging interdisciplinary approach to elucidate a mystery of remodeling process in nuclear architecture (Part II: Experiment)

Time 14:00 – 15:30, Sep. 9
Room B

The role of cost-benefit analysis in medicine

Organizer:

  • Shingo Iwami
    Department of Biology, Kyushu University

To inform the audience of recent advances in our understanding of the cost-benefit analysis in biology, we discuss how mathematical modeling can help decision-making in various practical situations. The symposium is designed to be a fine example of how, using mathematics in the context of cost-benefit studies, we can extract unique and novel information that helps advance the knowledge in a number of subfields in biology (e.g. ecology, epidemiology, virology, etc.).

Presenters and Titles:

Naoko Tomita

National Institute of Public Health

Health technology assessment and mathematical biology: A possibility for better economic evaluation

Eunha Shim

Soongsil University

Mathematica modeling vaccination against infectious diseases including dengue and influenza

Shingo Iwami

Kyushu University, JST PRESTO and CREST

Characterization of cost-effectiveness of multidrug treatment - Case study on HCV treatment

Time 14:00 – 15:30, Sep. 9
Room D

Real-time modeling approaches to vaccination and emerging infectious diseases
joint hosting symposium of The Toyota Physical and Chemical Research Institute, Specially Promoted Project

Organizers:

  • Kenji Mizumoto
    Hokkaido University
  • Hiroshi Nishiura
    Hokkaido University

It is increasingly recognized that real-time mathematical modeling plays a key role in clarifying the transmission dynamics of infectious diseases and estimating the effectiveness of interventions including immunization practice. This session aims to elaborate the formality of mathematical modeling of emerging infectious diseases and propagate the trend of real time modeling studies in the field of mathematical biology. A series of case studies on emerging infectious diseases including Middle East respiratory syndrome (MERS) and Zika virus infection are presented, along with modeling of vaccine preventable disease, especially vaccination against rubella is designed using a variety of mathematical models.

Presenters and Titles:

Kenji Mizumoto

Hokkaido University

Estimating Seasonal Influenza-Associated Deaths in Japan

Kyeongah Nah

Hokkaido University

Estimating risks of importation and local transmission of Zika virus infection

Ryo Kinoshita

Hokkaido University

Optimizing vaccination program against rubella in Japan

Ryota Matsuyama

Hokkaido University

A Meta-Analysis of Risk and Risk Factors related mortality of Middle East Respiratory syndrome

Masaya Saitoh

Institute of Statistical Mathematics

Spatiotemporal forecasting of rubella and its vaccination

Time 14:00 – 15:30, Sep. 9
Room E

Special symposium

Wanders will never cease: the current and future studies of the evolutionary ecology of dispersal

Organizers:

  • Ryosuke Iritani
    Kyushu University
  • Yuuya Tachiki
    Kyoto University

Dispersal and migration influence arrays of ecological setups of organisms, from allelic distribution to community compositions. Dispersal is, at the same time, subject to diverse selective pressures, and thus an evolving trait by natural selection (e.g., kin competition, sib-mating avoidance, resource heterogeneity). Therefore, studies on evolutionary ecology of dispersal and migration have been of pivotal importance in population ecology. In the present symposium, we review our current understandings of dispersal and migration from evolutionary and ecological points. Specifically, we illustrate different theoretical approaches to model the evolution of dispersal and migration. Each speaker briefly reviews their recent projects, and highlight the future directions and steps to enhance the elaboration of studies of dispersal.

Presenters and Titles:

Ryosuke, Iritani

Kyushu University

Who escapes from whom: disease transmission among kin can drive the evolution of conditional dispersal in viscous host populations

Florence, Débarre

College de France, France

Evolution of dispersal in spatially and temporally heterogeneous environments

Allison, K. Shaw

University of Minnesota

The evolution of marine larval dispersal kernels in spatially structured habitats

Yuuya Tachiki

Kyoto University

Evolutionary and ecological consequences of individual decisions, whether they stay or go, under environmental fluctuations